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Mesenchymal stromal cells cultured in physiological conditions sustain citrate secretion with glutamate anaplerosis

Bone marrow mesenchymal stromal cells (MSCs) have immunomodulatory and regenerative potential. However, culture conditions govern their metabolic processes and therapeutic efficacy. Here we show that culturing donor-derived MSCs in Plasmax™, a physiological medium with the concentrations of nutrient...

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Detalles Bibliográficos
Autores principales: Taurino, Giuseppe, Deshmukh, Ruhi, Villar, Victor H., Chiu, Martina, Shaw, Robin, Hedley, Ann, Shokry, Engy, Sumpton, David, Dander, Erica, D'Amico, Giovanna, Bussolati, Ovidio, Tardito, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254159/
https://www.ncbi.nlm.nih.gov/pubmed/35752287
http://dx.doi.org/10.1016/j.molmet.2022.101532