Dopamine‐related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth‐derived stem cells of children with Down syndrome

Down syndrome (DS) is one of the common genetic disorders caused by the trisomy of human chromosome 21 (HSA21). Mitochondrial dysfunction and redox imbalance play important roles in DS pathology, and altered dopaminergic regulation has been demonstrated in the brain of individuals with DS. However,...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Kato, Hiroki, Sato, Hiroshi, Han, Xu, Hirofuji, Yuta, Kato, Takahiro A., Sakai, Yasunari, Ohga, Shouichi, Fukumoto, Satoshi, Masuda, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254221/
https://www.ncbi.nlm.nih.gov/pubmed/35812076
http://dx.doi.org/10.1096/fba.2021-00086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254221/
https://www.ncbi.nlm.nih.gov/pubmed/35812076
http://dx.doi.org/10.1096/fba.2021-00086

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