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Dopamine‐related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth‐derived stem cells of children with Down syndrome
Down syndrome (DS) is one of the common genetic disorders caused by the trisomy of human chromosome 21 (HSA21). Mitochondrial dysfunction and redox imbalance play important roles in DS pathology, and altered dopaminergic regulation has been demonstrated in the brain of individuals with DS. However,...
Autores principales: | Sun, Xiao, Kato, Hiroki, Sato, Hiroshi, Han, Xu, Hirofuji, Yuta, Kato, Takahiro A., Sakai, Yasunari, Ohga, Shouichi, Fukumoto, Satoshi, Masuda, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254221/ https://www.ncbi.nlm.nih.gov/pubmed/35812076 http://dx.doi.org/10.1096/fba.2021-00086 |
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