ToxCast chemical library Wnt screen identifies diethanolamine as an activator of neural progenitor proliferation

Numerous autism spectrum disorder (ASD) risk genes are associated with Wnt signaling, suggesting that brain development may be especially sensitive to genetic perturbation of this pathway. Additionally, valproic acid, which modulates Wnt signaling, increases risk for ASD when taken during pregnancy....

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Detalles Bibliográficos
Autores principales: Wolter, Justin M., Jimenez, Jessica A., Stein, Jason L., Zylka, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254222/
https://www.ncbi.nlm.nih.gov/pubmed/35812078
http://dx.doi.org/10.1096/fba.2021-00163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254222/
https://www.ncbi.nlm.nih.gov/pubmed/35812078
http://dx.doi.org/10.1096/fba.2021-00163

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