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ToxCast chemical library Wnt screen identifies diethanolamine as an activator of neural progenitor proliferation
Numerous autism spectrum disorder (ASD) risk genes are associated with Wnt signaling, suggesting that brain development may be especially sensitive to genetic perturbation of this pathway. Additionally, valproic acid, which modulates Wnt signaling, increases risk for ASD when taken during pregnancy....
Autores principales: | Wolter, Justin M., Jimenez, Jessica A., Stein, Jason L., Zylka, Mark J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254222/ https://www.ncbi.nlm.nih.gov/pubmed/35812078 http://dx.doi.org/10.1096/fba.2021-00163 |
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