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Hsp40 overexpression in pacemaker neurons delays circadian dysfunction in a Drosophila model of Huntington's disease

Circadian disturbances are early features of neurodegenerative diseases, including Huntington's disease (HD). Emerging evidence suggests that circadian decline feeds into neurodegenerative symptoms, exacerbating them. Therefore, we asked whether known neurotoxic modifiers can suppress circadian...

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Detalles Bibliográficos
Autores principales: Prakash, Pavitra, Pradhan, Arpit Kumar, Sheeba, Vasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254228/
https://www.ncbi.nlm.nih.gov/pubmed/35645202
http://dx.doi.org/10.1242/dmm.049447