Acellular cardiac scaffolds enriched with MSC-derived extracellular vesicles limit ventricular remodelling and exert local and systemic immunomodulation in a myocardial infarction porcine model

Rationale: Extracellular vesicles (EVs) from mesenchymal stromal cell (MSC) are a potential therapy for cardiac healing after myocardial infarction (MI). Nevertheless, neither their efficient administration nor therapeutic mechanisms are fully elucidated. Here, we evaluate the preclinical efficacy o...

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Detalles Bibliográficos
Autores principales: Monguió-Tortajada, Marta, Prat-Vidal, Cristina, Martínez-Falguera, Daina, Teis, Albert, Soler-Botija, Carolina, Courageux, Yvan, Munizaga-Larroudé, Micaela, Moron-Font, Miriam, Bayes-Genis, Antoni, Borràs, Francesc E., Roura, Santiago, Gálvez-Montón, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254233/
https://www.ncbi.nlm.nih.gov/pubmed/35832072
http://dx.doi.org/10.7150/thno.72289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254233/
https://www.ncbi.nlm.nih.gov/pubmed/35832072
http://dx.doi.org/10.7150/thno.72289

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