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Acellular cardiac scaffolds enriched with MSC-derived extracellular vesicles limit ventricular remodelling and exert local and systemic immunomodulation in a myocardial infarction porcine model
Rationale: Extracellular vesicles (EVs) from mesenchymal stromal cell (MSC) are a potential therapy for cardiac healing after myocardial infarction (MI). Nevertheless, neither their efficient administration nor therapeutic mechanisms are fully elucidated. Here, we evaluate the preclinical efficacy o...
Autores principales: | Monguió-Tortajada, Marta, Prat-Vidal, Cristina, Martínez-Falguera, Daina, Teis, Albert, Soler-Botija, Carolina, Courageux, Yvan, Munizaga-Larroudé, Micaela, Moron-Font, Miriam, Bayes-Genis, Antoni, Borràs, Francesc E., Roura, Santiago, Gálvez-Montón, Carolina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254233/ https://www.ncbi.nlm.nih.gov/pubmed/35832072 http://dx.doi.org/10.7150/thno.72289 |
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