Internally inlaid SaCas9 base editors enable window specific base editing

Rationale: Base editors composed of catalytic defective Cas9 and cytosine or adenosine deaminase are powerful tools to convert bases in a genome. However, the fixed and narrow editing window of current base editors has impeded their utility. To increase the scope and diversify the editing patterns i...

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Detalles Bibliográficos
Autores principales: Jiang, Lurong, Long, Jie, Yang, Yang, Zhou, Lifang, Su, Jing, Qin, Fengming, Tang, Wenling, Tao, Rui, Chen, Qiang, Yao, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254239/
https://www.ncbi.nlm.nih.gov/pubmed/35832085
http://dx.doi.org/10.7150/thno.70869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254239/
https://www.ncbi.nlm.nih.gov/pubmed/35832085
http://dx.doi.org/10.7150/thno.70869

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