N(6)-methyladenosine-mediated LDHA induction potentiates chemoresistance of colorectal cancer cells through metabolic reprogramming

Background: Chemoresistance to 5-fluorouracil (5-FU) is a major barrier to influence the treatment efficiency of colorectal cancer (CRC) patients, while the precise molecular mechanisms underlying 5-FU resistance remain to be fully elucidated. Methods: The metabolic profiles including ATP generation...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Zhang, Tao, Yang, Yuhan, Tu, Wenling, Huang, Hongbin, Wang, Yujun, Chen, Yuzhuo, Pan, Kejian, Chen, Zhuojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254245/
https://www.ncbi.nlm.nih.gov/pubmed/35832094
http://dx.doi.org/10.7150/thno.73746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254245/
https://www.ncbi.nlm.nih.gov/pubmed/35832094
http://dx.doi.org/10.7150/thno.73746

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