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NOTCH1 signaling regulates the latent neurogenic program in adult reactive astrocytes after spinal cord injury

Background: Direct reprogramming of astrocytes into neurons opens up a new avenue for neuroregenerative medicine. However, the poor understanding of the molecular mechanisms underpinning the latent neurogenic program in astrocytes has largely restricted this strategy towards safe and effective clini...

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Detalles Bibliográficos
Autores principales: Tan, Zijian, Qin, Shangyao, Yuan, Yimin, Hu, Xin, Huang, Xiao, Liu, Hong, Pu, Yingyan, He, Cheng, Su, Zhida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254256/
https://www.ncbi.nlm.nih.gov/pubmed/35832093
http://dx.doi.org/10.7150/thno.71378