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A glance at post-translational modifications of human thyroglobulin: potential impact on function and pathogenesis

Thyroid hormones are essential for the metabolism of vertebrates and their synthesis, storage and release in the thyroid gland are orchestrated by their large protein precursor thyroglobulin (Tg). Alterations of Tg structure and localisation often correlate with major thyroid disorders. Namely, Tg i...

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Detalles Bibliográficos
Autores principales: Tosatto, Laura, Coscia, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254275/
https://www.ncbi.nlm.nih.gov/pubmed/35544053
http://dx.doi.org/10.1530/ETJ-22-0046