Effects of statins on the inducible degrader of low-density lipoprotein receptor in familial hypercholesterolemia

The inducible degrader of low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase involved in the post-transcriptional regulation of LDL receptor (LDLR). Statins lower plasma LDL by activating transcription of hepatic LDLR expression, and we have determined whether statins modulate IDOL ex...

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Detalles Bibliográficos
Autores principales: Chan, Melody Lok-Yi, Shiu, Sammy Wing-Ming, Cheung, Ching-Lung, Yu-Hung Leung, Anskar, Tan, Kathryn Choon-Beng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254294/
https://www.ncbi.nlm.nih.gov/pubmed/35560019
http://dx.doi.org/10.1530/EC-22-0019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254294/
https://www.ncbi.nlm.nih.gov/pubmed/35560019
http://dx.doi.org/10.1530/EC-22-0019

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