Cargando…

Effects of statins on the inducible degrader of low-density lipoprotein receptor in familial hypercholesterolemia

The inducible degrader of low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase involved in the post-transcriptional regulation of LDL receptor (LDLR). Statins lower plasma LDL by activating transcription of hepatic LDLR expression, and we have determined whether statins modulate IDOL ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chan, Melody Lok-Yi, Shiu, Sammy Wing-Ming, Cheung, Ching-Lung, Yu-Hung Leung, Anskar, Tan, Kathryn Choon-Beng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254294/ https://www.ncbi.nlm.nih.gov/pubmed/35560019 http://dx.doi.org/10.1530/EC-22-0019

Ejemplares similares

Genetic variations in familial hypercholesterolemia and cascade screening in East Asians
por: Chan, Melody Lok‐Yi, et al.
Publicado: (2018)

Familial hypercholesterolemia class II low-density lipoprotein receptor response to statin treatment
por: Omer, Linda, et al.
Publicado: (2020)

Effect of type 2 diabetes on the inducible degrader of LDL receptor
por: Lam, Sum, et al.
Publicado: (2023)

Effect of type 2 diabetes on A disintegrin and metalloprotease 10
por: Lam, Sum, et al.
Publicado: (2022)

Of statins and low-density lipoprotein cholesterol, “fats” and fiction
por: Unnikrishnan, Ambika Gopalakrishnan, et al.
Publicado: (2016)

Decreased Efficiency of Very-Low-Density Lipoprotein Lipolysis Is Linked to Both Hypertriglyceridemia and Hypercholesterolemia, but It Can Be Counteracted by High-Density Lipoprotein
por: Wieczorek, Ewa, et al.
Publicado: (2021)

Familial Hypercholesterolemia and Lipoprotein Apheresis
por: Makino, Hisashi, et al.
Publicado: (2019)

Lipoprotein metabolism in familial hypercholesterolemia
por: Chemello, Kévin, et al.
Publicado: (2021)

The Knowns and Unknowns of Contemporary Statin Therapy for Familial Hypercholesterolemia
por: Pang, Jing, et al.
Publicado: (2020)

Pregnancy in a Woman with Homozygous Familial Hypercholesterolemia Not on Low-Density Lipoprotein Apheresis
por: Fahed, Akl C., et al.
Publicado: (2012)

Systematic Review of Low‐Density Lipoprotein Cholesterol Apheresis for the Treatment of Familial Hypercholesterolemia
por: Wang, Anthony, et al.
Publicado: (2016)

Does low-density lipoprotein fully explain atherosclerotic risk in familial hypercholesterolemia?
por: Clarke, Shoa L.
Publicado: (2023)

Cholesterol efflux capacity of high‐density lipoprotein was not associated with cognitive decline and brain structures in older people with diabetes mellitus
por: Wu, Yuanyuan, et al.
Publicado: (2022)

Hypercholesterolemia, low density lipoprotein receptor and proprotein convertase subtilisin/kexin-type 9
por: Gu, Hong-mei, et al.
Publicado: (2015)

Statins but not fibrates improve the atherogenic to anti-atherogenic lipoprotein particle ratio: a randomized crossover study
por: Chan, Sammy Y, et al.
Publicado: (2008)

Long-term lipoprotein apheresis in the treatment of severe familial hypercholesterolemia refractory to high intensity statin therapy: Three year experience at a lipoprotein apheresis center
por: Mickiewicz, Agnieszka, et al.
Publicado: (2020)

Effect of bempedoic acid plus ezetimibe fixed-dose combination vs ezetimibe or placebo on low-density lipoprotein cholesterol in patients with type 2 diabetes and hypercholesterolemia not treated with statins
por: Bays, Harold E., et al.
Publicado: (2021)

Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia
por: Trinder, Mark, et al.
Publicado: (2020)

Analysis of the low density lipoprotein receptor gene (LDLR) mutation spectrum in Russian familial hypercholesterolemia
por: Vasilyev, V.B., et al.
Publicado: (2022)

Low-density lipoprotein receptor genotypes modify the sera metabolome of patients with homozygous familial hypercholesterolemia
por: Du, Zhiyong, et al.
Publicado: (2022)

The combination of Ezetimibe and Statin: a new treatment for hypercholesterolemia
por: NODARI, SAVINA, et al.
Publicado: (2007)

Combination therapy of statin and ezetimibe for the treatment of familial hypercholesterolemia
por: Hamilton-Craig, Ian, et al.
Publicado: (2010)

The Benefits Outweigh the Risks of Treating Hypercholesterolemia: The Statin Dilemma
por: Hussain, Azhar, et al.
Publicado: (2023)

Effects of Statins on High-Density Lipoproteins: A Potential Contribution to Cardiovascular Benefit
por: McTaggart, Fergus, et al.
Publicado: (2008)

Emerging Non-statin Treatment Options for Lowering Low-Density Lipoprotein Cholesterol
por: Bardolia, Chandni, et al.
Publicado: (2021)

Familial Resemblance in Low‐Density Lipoprotein Cholesterol Response to Statins in the Danish Population
por: Corn, Giulia, et al.
Publicado: (2022)

Low-density lipoprotein cholesterol, statin therapy, and cerebral microbleeds: The CIRCLE study
por: Zhao, Yuqi, et al.
Publicado: (2023)

Analysis of sequence variations in low-density lipoprotein receptor gene among Malaysian patients with familial hypercholesterolemia
por: Al-Khateeb, Alyaa, et al.
Publicado: (2011)

Expression of low density lipoprotein receptors in lymphoblasts induced by anti-CD3 antibody in patients with hypercholesterolemia.
por: Shin, B. M., et al.
Publicado: (1995)

Identification and Functional Characterization of a Low-Density Lipoprotein Receptor Gene Pathogenic Variant in Familial Hypercholesterolemia
por: Shu, Hong-Yan, et al.
Publicado: (2021)

Statin therapy in patients with acute coronary syndrome: low-density lipoprotein cholesterol goal attainment and effect of statin potency
por: Chinwong, Dujrudee, et al.
Publicado: (2015)

Baseline low-density lipoprotein cholesterol predicts the benefit of adding ezetimibe on statin in statin-naïve acute coronary syndrome
por: Im, Jihaeng, et al.
Publicado: (2021)

Early efficacy and safety of statin therapy in Korean patients with hypercholesterolemia: Daegu and Gyeongbuk Statin Registry
por: Bae, Han Joon, et al.
Publicado: (2020)

Statin Treatments And Dosages In Children With Familial Hypercholesterolemia: Meta-Analysis
por: Radaelli, Graciane, et al.
Publicado: (2018)

Efficacy and Safety of Bempedoic Acid in Patients With Hypercholesterolemia and Statin Intolerance
por: Laufs, Ulrich, et al.
Publicado: (2019)

Hypercholesterolemia and COVID-19: Statins for Lowering the Risk of Venous Thromboembolism
por: Vuorio, Alpo, et al.
Publicado: (2021)

Association of Familial Hypercholesterolemia and Statin Use With Risk of Dementia in Norway
por: Mundal, Liv J., et al.
Publicado: (2022)

Inclisiran adjuvant therapy to statins for the use of hypercholesterolemia: a commentary
por: Vohra, Laiba Imran, et al.
Publicado: (2023)

Low Levels of Low-Density Lipoprotein Cholesterol and Mortality Outcomes in Non-Statin Users
por: Sung, Ki-Chul, et al.
Publicado: (2019)

Statin therapy reduces oxidized low density lipoprotein level, a risk factor for stroke outcome
por: Tsai, Nai-Wen, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_i1tocm87phgm99644ed57unrgd