Single-cell sequencing reveals CD133(+)CD44(−)-originating evolution and novel stemness related variants in human colorectal cancer

BACKGROUND: Tumor heterogeneity of human colorectal cancer (CRC)-initiating cells (CRCICs) in cancer tissues often represents aggressive features of cancer progression. For high-resolution examination of CRCICs, we performed single-cell whole-exome sequencing (scWES) and bulk cell targeted exome seq...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyan, Yang, Ling, Lei, Wanjun, Hou, Qiang, Huang, Ming, Zhou, Rongjing, Enver, Tariq, Wu, Shixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254347/
https://www.ncbi.nlm.nih.gov/pubmed/35785618
http://dx.doi.org/10.1016/j.ebiom.2022.104125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254347/
https://www.ncbi.nlm.nih.gov/pubmed/35785618
http://dx.doi.org/10.1016/j.ebiom.2022.104125

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