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Ultrasound-triggered oxygen-loaded nanodroplets enhance and monitor cerebral damage from sonodynamic therapy

In sonodynamic therapy, cellular toxicity from sonosensitizer drugs, such as 5-aminolevulinic acid hydrochloride (5-ALA), may be triggered with focused ultrasound through the production of reactive oxygen species (ROS). Here we show that by increasing local oxygen during treatment, using oxygen-load...

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Detalles Bibliográficos
Autores principales: Lea-Banks, Harriet, Wu, Sheng-Kai, Lee, Hannah, Hynynen, Kullervo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254362/
https://www.ncbi.nlm.nih.gov/pubmed/35795341
http://dx.doi.org/10.7150/ntno.71946