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Interleukin-2 expands neuroprotective regulatory T cells in Parkinson’s disease

BACKGROUND: Pharmacological approaches that boost neuroprotective regulatory T cell (Treg) number and function lead to neuroprotective activities in neurodegenerative disorders. OBJECTIVES: We investigated whether low-dose interleukin 2 (IL-2) expands Treg populations and protects nigrostriatal dopa...

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Detalles Bibliográficos
Autores principales: Markovic, Milica, Yeapuri, Pravin, Namminga, Krista L., Lu, Yaman, Saleh, Maamoon, Olson, Katherine E., Gendelman, Howard E., Mosley, R. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254387/
http://dx.doi.org/10.1515/nipt-2022-0001