Repurposing Oxiconazole against Colorectal Cancer via PRDX2-mediated Autophagy Arrest

Colorectal cancer (CRC) is one of the most common malignancies worldwide, yet successful treatment still remains a challenge. In this study, we found that oxiconazole (OXI), a broad-spectrum antifungal agent, exhibits certain anti-tumor effect against CRC. Autophagy arrest and subsequent apoptosis a...

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Detalles Bibliográficos
Autores principales: Shi, Jinyu, Zhou, Li, Huang, Hui-Si, Peng, Liyuan, Xie, Na, Nice, Edouard, Fu, Li, Jiang, Cen, Huang, Canhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254464/
https://www.ncbi.nlm.nih.gov/pubmed/35813474
http://dx.doi.org/10.7150/ijbs.70679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254464/
https://www.ncbi.nlm.nih.gov/pubmed/35813474
http://dx.doi.org/10.7150/ijbs.70679

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