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Repurposing Oxiconazole against Colorectal Cancer via PRDX2-mediated Autophagy Arrest
Colorectal cancer (CRC) is one of the most common malignancies worldwide, yet successful treatment still remains a challenge. In this study, we found that oxiconazole (OXI), a broad-spectrum antifungal agent, exhibits certain anti-tumor effect against CRC. Autophagy arrest and subsequent apoptosis a...
Autores principales: | Shi, Jinyu, Zhou, Li, Huang, Hui-Si, Peng, Liyuan, Xie, Na, Nice, Edouard, Fu, Li, Jiang, Cen, Huang, Canhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254464/ https://www.ncbi.nlm.nih.gov/pubmed/35813474 http://dx.doi.org/10.7150/ijbs.70679 |
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