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R-loop Mapping and Characterization During Drosophila Embryogenesis Reveals Developmental Plasticity in R-loop Signatures

R-loops are involved in transcriptional regulation, DNA and histone post-translational modifications, genome replication and genome stability. To what extent R-loop abundance and genome-wide localization is actively regulated during metazoan embryogenesis is unknown. Drosophila embryogenesis provide...

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Detalles Bibliográficos
Autores principales: Munden, Alexander, Benton, Mary Lauren, Capra, John A., Nordman, Jared T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254486/
https://www.ncbi.nlm.nih.gov/pubmed/35609632
http://dx.doi.org/10.1016/j.jmb.2022.167645