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R-loop Mapping and Characterization During Drosophila Embryogenesis Reveals Developmental Plasticity in R-loop Signatures
R-loops are involved in transcriptional regulation, DNA and histone post-translational modifications, genome replication and genome stability. To what extent R-loop abundance and genome-wide localization is actively regulated during metazoan embryogenesis is unknown. Drosophila embryogenesis provide...
Autores principales: | Munden, Alexander, Benton, Mary Lauren, Capra, John A., Nordman, Jared T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254486/ https://www.ncbi.nlm.nih.gov/pubmed/35609632 http://dx.doi.org/10.1016/j.jmb.2022.167645 |
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