Reversal of cisplatin triggered neurotoxicity by Acacia hydaspica ethyl acetate fraction via regulating brain acetylcholinesterase activity, DNA damage, and pro-inflammatory cytokines in the rodent model

BACKGROUND: Cisplatin (CisPT) is a chemotherapeutic that outcome in adverse effects including neurotoxicity. We examined the efficacy of hydaspica ethyl acetate extract (AHE) against CisPT-prompted neurotoxicity. METHODS: Group I: Distilled water; Group II: CisPT (12 mg/kg b.w. i.p) on the 13(th) da...

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Detalles Bibliográficos
Autores principales: Afsar, Tayyaba, Razak, Suhail, Almajwal, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254489/
https://www.ncbi.nlm.nih.gov/pubmed/35790919
http://dx.doi.org/10.1186/s12906-022-03657-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254489/
https://www.ncbi.nlm.nih.gov/pubmed/35790919
http://dx.doi.org/10.1186/s12906-022-03657-3

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