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RNA interference protocol to silence oncogenic drivers in leukemia cell lines

Genetic silencing of leukemia-associated proteins with small interfering RNAs (siRNAs) is a straightforward way to delineate their functions. It can be very challenging to deliver siRNAs to leukemia-derived cells with high transfection efficiency and without compromising their viability. This protoc...

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Detalles Bibliográficos
Autores principales: Beyer, Mandy, Krämer, Oliver H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254495/
https://www.ncbi.nlm.nih.gov/pubmed/35779262
http://dx.doi.org/10.1016/j.xpro.2022.101512