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Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls

BACKGROUND: Multiple sclerosis (MS) is an autoimmune, neurodegenerative disorder with a strong genetic component that acts in a complex interaction with environmental factors for disease development. CD4(+) T cells are pivotal players in MS pathogenesis, where peripherally activated T cells migrate...

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Detalles Bibliográficos
Autores principales: Cappelletti, Chiara, Eriksson, Anna, Brorson, Ina Skaara, Leikfoss, Ingvild S., Kråbøl, Oda, Høgestøl, Einar August, Vitelli, Valeria, Mjaavatten, Olav, Harbo, Hanne F., Berven, Frode, Bos, Steffan D., Berge, Tone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254507/
https://www.ncbi.nlm.nih.gov/pubmed/35790914
http://dx.doi.org/10.1186/s12014-022-09361-1