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Regulatory roles of alternative splicing at Ezh2 gene in mouse oocytes

BACKGROUND: Enhancer of zeste homologue 2 (EZH2), the core member of polycomb repressive complex 2 (PRC2), has multiple splicing modes and performs various physiological functions. However, function and mechanism of alternative splicing at Ezh2 exon 3 in reproduction are unknown. METHODS: We generat...

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Detalles Bibliográficos
Autores principales: Guo, Shi-meng, Liu, Xing-ping, Tian, Qing, Fei, Cai-feng, Zhang, Yi-ran, Li, Zhi-ming, Yin, Ying, He, Ximiao, Zhou, Li-quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254527/
https://www.ncbi.nlm.nih.gov/pubmed/35791029
http://dx.doi.org/10.1186/s12958-022-00962-x