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Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ(1-42)-induced Alzheimer’s disease mice and glutamate-injured HT22 cells

BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative disease. Ferroptosis plays a critical role in neurodegenerative diseases. Nuclear factor E2-related factor 2 (Nrf2) is considered an important factor in ferroptosis. Studies have demonstrated that salidroside has a potential therapeutic eff...

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Detalles Bibliográficos
Autores principales: Yang, Sixia, xie, Zeping, Pei, Tingting, zeng, Yi, Xiong, Qiaowu, Wei, Hui, Wang, Yong, Cheng, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254541/
https://www.ncbi.nlm.nih.gov/pubmed/35787281
http://dx.doi.org/10.1186/s13020-022-00634-3