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Individual and Synergistic Anti-Coronavirus Activities of SOCS1/3 Antagonist and Interferon α1 Peptides

Suppressors of Cytokine Signaling (SOCS) are intracellular proteins that negatively regulate the induction of cytokines. Amongst these, SOCS1 and SOCS3 are particularly involved in inhibition of various interferons. Several viruses have hijacked this regulatory pathway: by inducing SOCS1and 3 early...

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Detalles Bibliográficos
Autores principales: Ahmed, Chulbul M., Grams, Tristan R., Bloom, David C., Johnson, Howard M., Lewin, Alfred S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254576/
https://www.ncbi.nlm.nih.gov/pubmed/35799776
http://dx.doi.org/10.3389/fimmu.2022.902956