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Multi-Modal Single-Cell Sequencing Identifies Cellular Immunophenotypes Associated With Juvenile Dermatomyositis Disease Activity

Juvenile dermatomyositis (JDM) is a rare autoimmune condition with insufficient biomarkers and treatments, in part, due to incomplete knowledge of the cell types mediating disease. We investigated immunophenotypes and cell-specific genes associated with disease activity using multiplexed RNA and pro...

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Detalles Bibliográficos
Autores principales: Neely, Jessica, Hartoularos, George, Bunis, Daniel, Sun, Yang, Lee, David, Kim, Susan, Ye, Chun Jimmie, Sirota, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254730/
https://www.ncbi.nlm.nih.gov/pubmed/35799782
http://dx.doi.org/10.3389/fimmu.2022.902232