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A Molecularly Characterized Preclinical Platform of Subcutaneous Renal Cell Carcinoma (RCC) Patient-Derived Xenograft Models to Evaluate Novel Treatment Strategies

Renal cell carcinoma (RCC) is a kidney cancer with an onset mainly during the sixth or seventh decade of the patient’s life. Patients with advanced, metastasized RCC have a poor prognosis. The majority of patients develop treatment resistance towards Standard of Care (SoC) drugs within months. Tyros...

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Detalles Bibliográficos
Autores principales: Gürgen, Dennis, Becker, Michael, Dahlmann, Mathias, Flechsig, Susanne, Schaeffeler, Elke, Büttner, Florian A., Schmees, Christian, Bohnert, Regina, Bedke, Jens, Schwab, Matthias, Wendler, Johann J., Schostak, Martin, Jandrig, Burkhard, Walther, Wolfgang, Hoffmann, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254864/
https://www.ncbi.nlm.nih.gov/pubmed/35800063
http://dx.doi.org/10.3389/fonc.2022.889789