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Oncolytic adenovirus with MUC16-BiTE shows enhanced antitumor immune response by reversing the tumor microenvironment in PDX model of ovarian cancer

The improved survival rate of ovarian cancer (OC) is related to the action of infiltrating cytotoxic T lymphocytes (CTLs). Recently, oncolytic adenoviruses (OAds) have emerged as a key player in treating solid tumors; however, the immunosuppressive tumor microenvironment (TME) and the body-mediated...

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Detalles Bibliográficos
Autores principales: Wang, Qiuman, Ma, Xinyue, Wu, Huan, Zhao, Chen, Chen, Jingying, Li, Rongrong, Yan, Shi, Li, Yingwei, Zhang, Qing, Song, Kun, Yuan, Cunzhong, Kong, Beihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255048/
https://www.ncbi.nlm.nih.gov/pubmed/35800156
http://dx.doi.org/10.1080/2162402X.2022.2096362