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Characteristics of leukemic stem cells in acute leukemia and potential targeted therapies for their specific eradication

In acute myeloid leukemia (AML), a small cell population that contains stem cell features such as lack of differentiation, self-renewal potential, and drug resistance, can be identified. These so-called leukemic stem cells (LSCs) are thought to be responsible for relapse initiation after initial tre...

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Detalles Bibliográficos
Autores principales: Hansen, Quinty, Bachas, Costa, Smit, Linda, Cloos, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255252/
https://www.ncbi.nlm.nih.gov/pubmed/35800375
http://dx.doi.org/10.20517/cdr.2021.140