Altered subgenomic RNA abundance provides unique insight into SARS-CoV-2 B.1.1.7/Alpha variant infections

B.1.1.7 lineage SARS-CoV-2 is more transmissible, leads to greater clinical severity, and results in modest reductions in antibody neutralization. Subgenomic RNA (sgRNA) is produced by discontinuous transcription of the SARS-CoV-2 genome. Applying our tool (periscope) to ARTIC Network Oxford Nanopor...

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Detalles Bibliográficos
Autores principales: Parker, Matthew D., Stewart, Hazel, Shehata, Ola M., Lindsey, Benjamin B., Shah, Dhruv R., Hsu, Sharon, Keeley, Alexander J., Partridge, David G., Leary, Shay, Cope, Alison, State, Amy, Johnson, Katie, Ali, Nasar, Raghei, Rasha, Heffer, Joe, Smith, Nikki, Zhang, Peijun, Gallis, Marta, Louka, Stavroula F., Hornsby, Hailey R., Alamri, Hatoon, Whiteley, Max, Foulkes, Benjamin H., Christou, Stella, Wolverson, Paige, Pohare, Manoj, Hansford, Samantha E., Green, Luke R., Evans, Cariad, Raza, Mohammad, Wang, Dennis, Firth, Andrew E., Edgar, James R., Gaudieri, Silvana, Mallal, Simon, Collins, Mark O., Peden, Andrew A., de Silva, Thushan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255483/
https://www.ncbi.nlm.nih.gov/pubmed/35790808
http://dx.doi.org/10.1038/s42003-022-03565-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255483/
https://www.ncbi.nlm.nih.gov/pubmed/35790808
http://dx.doi.org/10.1038/s42003-022-03565-9

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