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Human transfer RNA modopathies: diseases caused by aberrations in transfer RNA modifications

tRNA molecules are post‐transcriptionally modified by tRNA modification enzymes. Although composed of different chemistries, more than 40 types of human tRNA modifications play pivotal roles in protein synthesis by regulating tRNA structure and stability as well as decoding genetic information on mR...

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Detalles Bibliográficos
Autores principales: Chujo, Takeshi, Tomizawa, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255597/
https://www.ncbi.nlm.nih.gov/pubmed/33513290
http://dx.doi.org/10.1111/febs.15736