Applying the AFRAID and FRIGHT Clocks to Novel Preclinical Mouse Models of Polypharmacy

The Frailty Inferred Geriatric Health Timeline (FRIGHT) and Analysis of Frailty and Death (AFRAID) clocks were developed to predict biological age and lifespan, respectively, in mice. Their utility within the context of polypharmacy (≥5 medications), which is very common in older adults, is unknown....

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Detalles Bibliográficos
Autores principales: Mach, John, Kane, Alice E, Howlett, Susan E, Sinclair, David A, Hilmer, Sarah N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255695/
https://www.ncbi.nlm.nih.gov/pubmed/35313348
http://dx.doi.org/10.1093/gerona/glac067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255695/
https://www.ncbi.nlm.nih.gov/pubmed/35313348
http://dx.doi.org/10.1093/gerona/glac067

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