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Applying the AFRAID and FRIGHT Clocks to Novel Preclinical Mouse Models of Polypharmacy
The Frailty Inferred Geriatric Health Timeline (FRIGHT) and Analysis of Frailty and Death (AFRAID) clocks were developed to predict biological age and lifespan, respectively, in mice. Their utility within the context of polypharmacy (≥5 medications), which is very common in older adults, is unknown....
Autores principales: | Mach, John, Kane, Alice E, Howlett, Susan E, Sinclair, David A, Hilmer, Sarah N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255695/ https://www.ncbi.nlm.nih.gov/pubmed/35313348 http://dx.doi.org/10.1093/gerona/glac067 |
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