Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis

Intracellular pathogens secrete effectors to manipulate their host cells. Histoplasma capsulatum (Hc) is a fungal intracellular pathogen of humans that grows in a yeast form in the host. Hc yeasts are phagocytosed by macrophages, where fungal intracellular replication precedes macrophage lysis. The...

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Detalles Bibliográficos
Autores principales: Azimova, Dinara, Herrera, Nadia, Duvenage, Lucian, Voorhies, Mark, Rodriguez, Rosa A., English, Bevin C., Hoving, Jennifer C., Rosenberg, Oren, Sil, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255746/
https://www.ncbi.nlm.nih.gov/pubmed/35731824
http://dx.doi.org/10.1371/journal.ppat.1010417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255746/
https://www.ncbi.nlm.nih.gov/pubmed/35731824
http://dx.doi.org/10.1371/journal.ppat.1010417

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