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Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses

De novo initiation by viral RNA-dependent RNA polymerases often requires a polymerase priming residue, located within a priming loop, to stabilize the initiating NTPs. Polymerase structures from three different non-segmented negative strand RNA virus (nsNSV) families revealed putative priming loops...

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Detalles Bibliográficos
Autores principales: Cressey, Tessa N., Shareef, Afzaal M., Kleiner, Victoria A., Noton, Sarah L., Byrne, Patrick O., McLellan, Jason S., Mühlberger, Elke, Fearns, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255747/
https://www.ncbi.nlm.nih.gov/pubmed/35731802
http://dx.doi.org/10.1371/journal.ppat.1010451