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Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses
De novo initiation by viral RNA-dependent RNA polymerases often requires a polymerase priming residue, located within a priming loop, to stabilize the initiating NTPs. Polymerase structures from three different non-segmented negative strand RNA virus (nsNSV) families revealed putative priming loops...
Autores principales: | Cressey, Tessa N., Shareef, Afzaal M., Kleiner, Victoria A., Noton, Sarah L., Byrne, Patrick O., McLellan, Jason S., Mühlberger, Elke, Fearns, Rachel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255747/ https://www.ncbi.nlm.nih.gov/pubmed/35731802 http://dx.doi.org/10.1371/journal.ppat.1010451 |
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