Cargando…

Avidity in antibody effector functions and biotherapeutic drug design

Antibodies are the cardinal effector molecules of the immune system and are being leveraged with enormous success as biotherapeutic drugs. A key part of the adaptive immune response is the production of an epitope-diverse, polyclonal antibody mixture that is capable of neutralizing invading pathogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Oostindie, Simone C., Lazar, Greg A., Schuurman, Janine, Parren, Paul W. H. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255845/
https://www.ncbi.nlm.nih.gov/pubmed/35790857
http://dx.doi.org/10.1038/s41573-022-00501-8