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Avidity in antibody effector functions and biotherapeutic drug design
Antibodies are the cardinal effector molecules of the immune system and are being leveraged with enormous success as biotherapeutic drugs. A key part of the adaptive immune response is the production of an epitope-diverse, polyclonal antibody mixture that is capable of neutralizing invading pathogen...
Autores principales: | Oostindie, Simone C., Lazar, Greg A., Schuurman, Janine, Parren, Paul W. H. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255845/ https://www.ncbi.nlm.nih.gov/pubmed/35790857 http://dx.doi.org/10.1038/s41573-022-00501-8 |
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