Genome-wide detection of imprinted differentially methylated regions using nanopore sequencing

Imprinting is a critical part of normal embryonic development in mammals, controlled by defined parent-of-origin (PofO) differentially methylated regions (DMRs) known as imprinting control regions. Direct nanopore sequencing of DNA provides a means to detect allelic methylation and to overcome the d...

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Detalles Bibliográficos
Autores principales: Akbari, Vahid, Garant, Jean-Michel, O'Neill, Kieran, Pandoh, Pawan, Moore, Richard, Marra, Marco A, Hirst, Martin, Jones, Steven JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255983/
https://www.ncbi.nlm.nih.gov/pubmed/35787786
http://dx.doi.org/10.7554/eLife.77898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255983/
https://www.ncbi.nlm.nih.gov/pubmed/35787786
http://dx.doi.org/10.7554/eLife.77898

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