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Histopathologic effect of in ovo exposure to methotrexate at early embryonic stage on optic tectum of Japanese quail (Coturnix japonica)

The optic tectum of Japanese quail embryos with in ovo exposure to methotrexate 100 ng/g egg on embryonic day 4 was examined from 3 to 24 hour after treatment. At 9 hour after methotrexate exposure, several apoptotic neuroepithelial cells appeared in the ventricular zone of the optic tectum; these i...

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Detalles Bibliográficos
Autores principales: Nohara, Masakatsu, Iwasaki, Mayo, Nishio, Mahiro, Sugiyama, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256001/
https://www.ncbi.nlm.nih.gov/pubmed/35832899
http://dx.doi.org/10.1293/tox.2022-0011