The potential of organoids in toxicologic pathology: role of toxicologic pathologists in in vitro chemical hepatotoxicity assessment

The development of in vitro toxicity assessment methods using cultured cells has gained popularity for promoting animal welfare in animal experiments. Herein, we briefly discuss the current status of hepatoxicity assessment using human- and rat-derived hepatocytes; we focus on the liver organoid met...

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Detalles Bibliográficos
Autores principales: Yoshida, Toshinori, Kobayashi, Mio, Uomoto, Suzuka, Ohshima, Kanami, Hara, Emika, Katoh, Yoshitaka, Takahashi, Naofumi, Harada, Takanori, Usui, Tatsuya, Elbadawy, Mohamed, Shibutani, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2022
Materias:
Featured Article Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256002/
https://www.ncbi.nlm.nih.gov/pubmed/35832897
http://dx.doi.org/10.1293/tox.2022-0017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256002/
https://www.ncbi.nlm.nih.gov/pubmed/35832897
http://dx.doi.org/10.1293/tox.2022-0017

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