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The potential of organoids in toxicologic pathology: role of toxicologic pathologists in in vitro chemical hepatotoxicity assessment
The development of in vitro toxicity assessment methods using cultured cells has gained popularity for promoting animal welfare in animal experiments. Herein, we briefly discuss the current status of hepatoxicity assessment using human- and rat-derived hepatocytes; we focus on the liver organoid met...
Autores principales: | Yoshida, Toshinori, Kobayashi, Mio, Uomoto, Suzuka, Ohshima, Kanami, Hara, Emika, Katoh, Yoshitaka, Takahashi, Naofumi, Harada, Takanori, Usui, Tatsuya, Elbadawy, Mohamed, Shibutani, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256002/ https://www.ncbi.nlm.nih.gov/pubmed/35832897 http://dx.doi.org/10.1293/tox.2022-0017 |
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