A model of metformin mitochondrial metabolism in metachromatic leukodystrophy: first description of human Schwann cells transfected with CRISPR-Cas9

Metachromatic leukodystrophy is a neurological lysosomal deposit disease that affects public health despite its low incidence in the population. Currently, few reports are available on pathophysiological events related to enzyme deficiencies and subsequent sulfatide accumulation. This research aims...

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Detalles Bibliográficos
Autores principales: Sanchez-Álvarez, Nayibe Tatiana, Bautista-Niño, Paula Katherine, Trejos-Suárez, Juanita, Serrano-Díaz, Norma Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256087/
https://www.ncbi.nlm.nih.gov/pubmed/35857900
http://dx.doi.org/10.1098/rsob.210371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256087/
https://www.ncbi.nlm.nih.gov/pubmed/35857900
http://dx.doi.org/10.1098/rsob.210371

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