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ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge’s disease

At high altitude Andean region, hypoxia-induced excessive erythrocytosis (EE) is the defining feature of Monge’s disease or chronic mountain sickness (CMS). At the same altitude, resides a population that has developed adaptive mechanism(s) to constrain this hypoxic response (non-CMS). In this study...

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Detalles Bibliográficos
Autores principales: Azad, Priti, Caldwell, Andrew B., Ramachandran, Srinivasan, Spann, Nathanael J., Akbari, Ali, Villafuerte, Francisco C., Bermudez, Daniela, Zhao, Helen, Poulsen, Orit, Zhou, Dan, Bafna, Vineet, Subramaniam, Shankar, Haddad, Gabriel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256584/
https://www.ncbi.nlm.nih.gov/pubmed/35672450
http://dx.doi.org/10.1038/s12276-022-00769-1