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Resolving missing protein problems using functional class scoring

Despite technological advances in proteomics, incomplete coverage and inconsistency issues persist, resulting in “data holes”. These data holes cause the missing protein problem (MPP), where relevant proteins are persistently unobserved, or sporadically observed across samples, hindering biomarker d...

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Detalles Bibliográficos
Autores principales: Wong, Bertrand Jern Han, Kong, Weijia, Wong, Limsoon, Goh, Wilson Wen Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256666/
https://www.ncbi.nlm.nih.gov/pubmed/35790756
http://dx.doi.org/10.1038/s41598-022-15314-3