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Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy

Locally advanced cancers remain therapeutically challenging to eradicate. The most successful treatments continue to combine decades old non-targeted chemotherapies with radiotherapy that unfortunately increase normal tissue damage in the irradiated field and have systemic toxicities precluding furt...

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Detalles Bibliográficos
Autores principales: Hingorani, Dina V., Allevato, Michael M., Camargo, Maria F., Lesperance, Jacqueline, Quraishi, Maryam A., Aguilera, Joseph, Franiak-Pietryga, Ida, Scanderbeg, Daniel J., Wang, Zhiyong, Molinolo, Alfredo A., Alvarado, Diego, Sharabi, Andrew B., Bui, Jack D., Cohen, Ezra E. W., Adams, Stephen R., Gutkind, J. Silvio, Advani, Sunil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256669/
https://www.ncbi.nlm.nih.gov/pubmed/35790753
http://dx.doi.org/10.1038/s41467-022-31601-z