BCAT1 promotes osteoclast maturation by regulating branched-chain amino acid metabolism

Branched-chain aminotransferase 1 (BCAT1) transfers the amine group on branched-chain amino acids (BCAAs) to alpha-ketoglutarate. This generates glutamate along with alpha-keto acids that are eventually oxidized to provide the cell with energy. BCAT1 thus plays a critical role in sustaining BCAA con...

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Detalles Bibliográficos
Autores principales: Go, Miyeon, Shin, Eunji, Jang, Seo Young, Nam, Miso, Hwang, Geum-Sook, Lee, Soo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256685/
https://www.ncbi.nlm.nih.gov/pubmed/35760874
http://dx.doi.org/10.1038/s12276-022-00775-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256685/
https://www.ncbi.nlm.nih.gov/pubmed/35760874
http://dx.doi.org/10.1038/s12276-022-00775-3

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