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Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development

Mammalian pre-implantation embryos accumulate substantial lipids, which are stored in lipid droplets (LDs). Despite the fundamental roles of lipids in many cellular functions, the significance of building-up LDs for the developing embryo remains unclear. Here we report that the accumulation and mobi...

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Detalles Bibliográficos
Autores principales: Mau, King Hang Tommy, Karimlou, Donja, Barneda, David, Brochard, Vincent, Royer, Christophe, Leeke, Bryony, de Souza, Roshni A., Pailles, Mélanie, Percharde, Michelle, Srinivas, Shankar, Jouneau, Alice, Christian, Mark, Azuara, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256688/
https://www.ncbi.nlm.nih.gov/pubmed/35790717
http://dx.doi.org/10.1038/s41467-022-31323-2